ゲノム解読の裏側?暗黒タンパク質群とは【生命科学ニュース】 #たかとー研究室 #shorts

ゲノム解読の裏側?暗黒タンパク質群とは【生命科学ニュース】 #たかとー研究室 #shorts

【関連配信】
ゲノム解読の裏側?暗黒タンパク質群とは【生命科学ニュース】 #たかとー研究室

【原著論文】
High-quality peptide evidence for annotating non-canonical open reading frames as human proteins
https://www.biorxiv.org/content/10.1101/2024.09.09.612016v1

【動画制作】
茜ちえりさん
https://www.youtube.com/c/Chierisstudyroom

【参加者のTwitter, YouTube(参加順)】
私、高遠頼(合成生物学、バイオインフォマティクス)
@takatoh_life

#Vtuber
#生命科学
#暗黒タンパク質

【参考資料】
Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma
https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)01022-5

‘Dark proteome’ survey reveals thousands of new human genes
https://www.science.org/content/article/dark-proteome-survey-reveals-thousands-new-human-genes

‘Dark proteins’ hiding in our cells could hold clues to cancer and other diseases
https://www.nature.com/articles/d41586-025-00217-w

Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project
https://pubs.acs.org/doi/10.1021/acs.jproteome.8b00441
https://pmc.ncbi.nlm.nih.gov/articles/PMC6387656/

Noncanonical open reading frames encode functional proteins essential for cancer cell survival
https://www.nature.com/articles/s41587-020-00806-2
https://pmc.ncbi.nlm.nih.gov/articles/PMC8195866/

What Can Ribo-Seq, Immunopeptidomics, and Proteomics Tell Us About the Noncanonical Proteome?
https://www.mcponline.org/article/S1535-9476(23)00142-1/fulltext

Initial sequencing and analysis of the human genome
https://www.nature.com/articles/35057062

The Sequence of the Human Genome
https://www.science.org/doi/10.1126/science.1058040

The complete sequence of a human genome
https://www.science.org/doi/10.1126/science.abj6987

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